Tirzepatide is a GIP and GLP-1 receptor agonist and works for weight loss by decreasing your appetite and slowing the movement of food from the stomach into the small intestine, which may make you feel full more quickly and for a longer period of time. Tirzepatide also decreases blood sugar levels by increasing insulin production and lowering the amount of sugar the liver makes.
It's the first combination of 2 classes of medications, the GIP and GLP-1 receptor agonist which are both incretin hormones that are released after food intake.
Both GIP and GLP-1 receptors are found in areas of the human brain important for appetite regulation. Tirzepatide has been shown to decrease food intake and modulate fat utilization.
Tirzepatide works by mimicking both of these receptor agonists, which includes processes like alerting the pancreas to stop releasing insulin after eating and sending signals to the liver to decrease glucose levels.
In turn, this not only helps you feel fuller for longer but it slows down digestion, and aids in glycemic control, which all lead to weight loss and weight management.
People using Tirzepatide, have lost up to 25% of their body weight on average.
People using Tirzepatide, have lost up to 25% of their body weight on average.
Tirzepatide is indicated for chronic weight management in patients with a body mass index (BMI) of 27 kg/m2 or greater who have at least one weight-related ailment such as high blood pressure, Type 2 diabetes or high cholesterol OR in patients with a BMI of 30 kg/m2 or greater.
Those with a personal or family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 , or pancreatitis, may be disqualified from taking the medication.
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